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U.S. STOCKS ON THE MOVE-Pfizer, Delta, Relmada Therapeutics

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The S&P 500 and Nasdaq ended lower on Tuesday, with indications from the Bank of
England that it would support the country's bond market for just three more days
adding to market jitters. .N 
    At 7:38 AM ET, Dow e-minis  1YMc1  were up 0.68% at 29,460. S&P 500 e-minis
 ESc1  were up 0.68% at 3,612.75, while Nasdaq 100 e-minis  NQc1  were up 0.40%
at 10,884.25.
 
 The top three NYSE percentage gainers premarket  .PRPG.NQ :
 ** TopBuild Corp  BLD , up 8.3%
 ** Lloyds Banking Group plc  LYG , up 7.6%
 ** NatWest Group plc  NWG , up 7.2%
 
 The top three NYSE percentage losers premarket  .PRPL.NQ :
 ** ProPetro Holding Corp  PUMP.K , down 11.7%
 ** AMTD Digital Inc  HDK , down 7.7%
 ** A. O. Smith Corporation  AOS , down 7.5%
 
 The top three Nasdaq percentage gainers premarket  .PRPG.O :
 ** Laser Photonics Corp  LASE.O , up 46.8%
 ** Corbus Pharmaceuticals Holdings Inc  CRBP.O , up 27.8%
 ** VectivBio Holding AG  VECT.O , up 24.8%
    
 The top Nasdaq percentage losers premarket  .PRPL.O :
 ** Relmada Therapeutics Inc  RLMD.O , down 80%
 ** T2 Biosystems Inc  TTOO.O , down 22.9%
 
 ** Relmada Therapeutics Inc  RLMD.O : down 80% premarket
 BUZZ: Relmada Therapeutics sinks 80% as depression therapy fails  urn:newsml:reuters.com:*:nL4N30F3B7
    
 ** Digital World Acquisition Corp  DWAC.O : up 11.2% premarket
 BUZZ - Trump-linked SPAC gains as Truth Social goes live on Google Play Store
 urn:newsml:reuters.com:*:nL4N31E1TB
 ** Pfizer Inc  PFE.N : up 2.9% premarket
 BUZZ - Up after seeking nod for COVID booster shot for kids above 5 in Japan
 urn:newsml:reuters.com:*:nL4N31E21L
 ** Applied Materials Inc  AMAT.O : down 2.0% premarket
 BUZZ - Falls on forecast of hit from new export curbs  urn:newsml:reuters.com:*:nL4N31E1X1
 ** Astra Space Inc  ASTR.O : up 0.4% premarket
 BUZZ - Gains on second engine supply deal of week  urn:newsml:reuters.com:*:nL4N31E24U
 ** Doximity Inc  DOCS.N : down 1.0% premarket
 BUZZ - Ad spend for Doximity under pressure amid recession risk  urn:newsml:reuters.com:*:nL4N31E26J
 ** Delta Air Lines Inc  DAL.N : up 4.2% premarket
 BUZZ - Gains on expectations of higher Q4 revenue vs 2019 as demand improves
 urn:newsml:reuters.com:*:nL4N31E295
 ** Dice Therapeutics Inc  DICE.O : down 1.8% premarket
 BUZZ - Slips after pricing upsized $300 mln stock deal  urn:newsml:reuters.com:*:nL1N31E0ST
 (Compiled by Rajarshi Roy and Pratik Jain in Bengaluru)
 ((Rajarshi.Roy@thomssonreuters.com))

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